CD36 inhibition enhances the anti-proliferative effects of PI3K inhibitors in PTEN-loss anti-HER2 resistant breast cancer cells

Abstract Background HER2-positive patients comprise approximately 20% of breast cancer cases, with HER2-targeted therapy significantly improving progression-free and overall survival.However, subsequent reprogramed tumor progression due to PI3K signaling pathway activation by PIK3CA mutations and/or PTEN-loss cause anti-HER2 resistance.Previously,

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Differential-drive Mobile Robot Controller with ROS 2 Support

Autonomous Mobile Robots, known as AMRs, are used in the internal logistics of many types of industries and production sectors.This type of robots replaces the traditional Automated Guided Vehicles (AGVs).In the case of AGVs, the path to follow is previously defined, and these robots do not have the ability to choose a different path.On the other h

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Absolute Lymphocyte Count and its Correlation with Serum Ferritin Level: An early indicator of disease severity in COVID-19

Introduction: The massive number of cases with SARS-Cov-2 has put a tremendous pressure on healthcare systems all over the world.Most of the countries have declared health emergency.In these highly challenging times and also to reduce the risk of morbidity early warning signs may be helpful.6 Objective: To correlate lymphocyte count with serum ferr

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